Biologists join drive to turn down the lights

Signal Amplification: Let's Turn Down The Lights

G protein activation by membrane-bound receptors initiates a chain reaction that amplifies cellular responses to external signals. In retinal photoreceptors, amplification by the phototransduction cascade is regulated by quickly switching off the visual pigment that acts as the receptor for light.

Noncoding RNAs: 'our turn' to join the p53 network.

Please turn off the lights: the effectiveness of visual prompts.

Two early studies showed that visual prompts can be effectively used to encourage people to turn off the lights in unoccupied classrooms, but they were methodologically limited. The current study used an ABAB-B design with an 11-week follow-up to investigate whether two different visual prompts (large and small signs) could be employed to increase "lights off" behaviour in 17 unoccupied washroo...

tURn the Lights on: Mitochondrial Transport‐RNAs and Cardiovascular Disease

Introduction to Mitochondrial Genome M itochondria are the organelles universally known as the cellular power plants because they generate most of the cellular energy by oxidative phosphorylation. Moreover, mitochondria are involved in many other cellular activities, such as hormones and heme synthesis, calcium ions storage, and regulation of cellular proliferation and/or differentiation. The r...

Turn It Down a Notch

In the developing vertebrate embryo, segmentation initiates through the formation of repeated segments, or somites, on either side of the posterior neural tube along the anterior to posterior axis. The periodicity of somitogenesis is regulated by a molecular oscillator, the segmentation clock, driving cyclic gene expression in the unsegmented paraxial mesoderm, from which somites derive. Three ...